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Regardless of which way the label is facing, you want the line to come off of the filler spool in the same direction ( clockwise, or counter clockwise ) as the line goes on to the spool of your reel. You do not want them going opposite directions, nor do you want to let the filler spool turn on it's axis. Some people will put a pencil or something through the hub of the filler spool, and let the spool spin while they reel the line on to the spool of the reel. That will cause the line to twist too.