Another flyfisher who uses flouro almost exclusively for tippets.(last link from leader to hook). No refuting the fish don't see it as easily, usually you can go at least one size heavier than conventional mono. The knots can be tricky;as mentioned above wetting is mandatory, as is smooth tightening. I take one less turn on an improved clinch, and then check carefully. Don't lose many due to bad knots, but often have to retie.