The Laramie River Road is definitely closed in the winter, so you're not driving there from either Wyoming or Colorado.
As far as I know the best bet is to snowshoe or cross-country ski in via one of the campground roads off of Route 14 the Poudre Canyon Road.
(You could also go in my snowmobile off the Laramie River Road.)
There are Lakers (Mackinaws) in there, though nothing too big.