If anything, go a little larger on the pants, as the legs on the pants tend to run a bit small. I'm 6'4" and 220lb and just ordered the Arctic Armour Plus 2XL jacket and bibs, everything fits great, but the pant legs don't leave a ton of room for extra layers. If they're as warm as everyone says, then it shouldn't be an issue, otherwise I'll just have to wear my thinner underlayers.